Article
Structural analysis of a prototypical ATPase from the type III secretion system.
Nature structural & molecular biology - 1 Feb 2007
Zarivach Raz, Vuckovic Marija, Deng Wanyin, Finlay B Brett, Strynadka Natalie C J
Abstract excerpt
The type III secretion system (T3SS) ATPase is the conserved and essential inner-membrane component involved in the initial stages of selective secretion of specialized T3SS virulence effector proteins from the bacterial cytoplasm through to the infected host cell, a process crucial to subsequent pathogenicity. Here we present the 1.8-A-resolution crystal structure of the catalytic domain of the prototypical T3SS...
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