Article
Genomic characterization of multiple clinical phenotypes of cancer using multivariate linear regression models.
Bioinformatics (Oxford, England) - 15 Mar 2007
Matsui Shigeyuki, Ito Masaaki, Nishiyama Hiroyuki, Uno Hajime, Kotani Hirokazu, Watanabe Jun, Guilford Parry, Reeve Anthony, Fukushima Masanori, Ogawa Osamu
Abstract excerpt
MOTIVATION: The development of gene expression microarray technology has allowed the identification of differentially expressed genes between different clinical phenotypic classes of cancer from a large pool of candidate genes. Although many class comparisons concerned only a single phenotype, simultaneous assessment of the relationship between gene expression and multiple phenotypes would be warranted to better...
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