Article
Fimbrial lectins influence the chemokine repertoire in the urinary tract mucosa.
Kidney international - 1 Apr 2007
Godaly G, Otto G, Burdick M D, Strieter R M, Svanborg C
Abstract excerpt
The defense against mucosal infections relies on chemokines that recruit inflammatory cells to the mucosa. This study examined if the chemokine response to uro-pathogenic Escherichia coli is influenced by fimbrial expression. The CXC (CXCL1, CXCL5, CXCL8, CXCL9, CXCL10) and CC chemokines (CCL2, CCL3, CCL5) were quantified after in vitro infection of uro-epithelial cells with a fimbriated E. coli pyelonephritis...
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