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Article

Temporal target restriction of olfactory receptor neurons by Semaphorin-1a/PlexinA-mediated axon-axon interactions.

Neuron - 18 Jan 2007

Sweeney Lora B, Couto Africa, Chou Ya-Hui, Berdnik Daniela, Dickson Barry J, Luo Liqun, Komiyama Takaki

Abstract excerpt

Axon-axon interactions have been implicated in neural circuit assembly, but the underlying mechanisms are poorly understood. Here, we show that in the Drosophila antennal lobe, early-arriving axons of olfactory receptor neurons (ORNs) from the antenna are required for the proper targeting of late-arriving ORN axons from the maxillary palp (MP). Semaphorin-1a is required for targeting of all MP but only half of...

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PMID: 17224402
DOI: 10.1016/j.neuron.2006.12.022

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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