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Article

Genetic polymorphisms and treatment response in advanced non-small cell lung cancer.

Lung cancer (Amsterdam, Netherlands) - 1 May 2007

Su Dan, Ma Shenglin, Liu Peng, Jiang Zhiming, Lv Wangxia, Zhang Yimin, Deng Qinghua, Smith Stephanie, Yu Herbert

Abstract excerpt

BACKGROUND: Genetic polymorphisms involved in DNA repair and apoptosis are suspected to influence patient response to cancer treatment. To evaluate the effect of genetic variations on chemotherapy and/or radiotherapy, we genotyped four single nucleotide polymorphisms (SNPs) in ATM (A60G), ERCC1 (Asn118Asn), APE1 (Asn148Glu), and iASPP (A67T), and examined their associations with treatment response among patients...

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Source

Identifiers

PMID: 17222938
DOI: 10.1016/j.lungcan.2006.12.002

Genes

ERCC1
ATM

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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