Article
In Vitro Activity of API-1252, a Novel FabI Inhibitor, against Clinical Isolates of <i>Staphylococcus aureus</i> and <i>Staphylococcus epidermidis</i>
13 Jan 2007
Abstract excerpt
API-1252 (Fig. [1][1]), an inhibitor of bacterial enoyl-acyl carrier protein (enoyl-ACP) reductase (FabI), is being developed by Affinium Pharmaceuticals, Inc. (Toronto, Canada), in both oral and intravenous formulations, for single-agent and combination treatment of antimicrobial-susceptible and -
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