Article
An IGF-I gene polymorphism modifies the risk of developing persistent microalbuminuria in type 1 diabetes.
European journal of endocrinology - 1 Jan 2007
Hovind Peter, Lamberts Steven, Hop Wim, Deinum Jaap, Tarnow Lise, Parving Hans-Henrik, Janssen Joop A M J L
Abstract excerpt
OBJECTIVE: Derangements of the GH-IGF-I axis have been associated with microalbuminuria (MA) in type 1 diabetes. The aim of this study was to investigate whether an IGF-I gene promoter polymorphism influenced the development of persistent MA in type 1 diabetes. DESIGN: A prospective follow-up study of a cohort of 277 patients with newly diagnosed type 1 diabetes consecutively enrolled between September 1979 and...
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