Article
Colorimetric biosensors based on DNA-nanoparticle conjugates.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry - 1 Jan 2007
Sato Kae, Hosokawa Kazuo, Maeda Mizuo
Abstract excerpt
In this review, we present an overview of the technologies in colorimetric biosensors based on DNA-nanoparticle conjugates. Two types of DNA-nanoparticles aggregation assays are summarized. One of the methods relies on cross-linking of the gold nanoparticle (GNP) by hybridization. The crosslinking system was used not only to detect target DNA sequences, but also to detect metal ions or small molecules which were...
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