Article
Nuclear HBcAg and histology activity index as independent predictors of the expression of singly spliced HBV-RNA.
Journal of viral hepatitis - 1 Jan 2007
Sheen I-S, Tsou Y-K, Lin S-M, Lin C-J, Lin C-C, Hsu C-W, Chen Y-C, Chang M-L, Yeh C-T
Abstract excerpt
Although hepatitis B virus (HBV) RNA splicing has been reported by many researchers, the clinical significance of this event remains illusive. The present study was designed to investigate the clinical roles of singly spliced HBV-RNA. Liver biopsy tissues obtained from 32 consecutive patients were subjected to reverse transcriptase-polymerase chain reaction for the detection of singly spliced and unspliced...
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