Article
The quest for genes causing complex traits in ocular medicine: successes, interpretations, and challenges.
Archives of ophthalmology (Chicago, Ill. : 1960) - 1 Jan 2007
Iyengar Sudha K
Abstract excerpt
Gene mapping and positional cloning have gained acceptance as state-of-the-art methods to identify molecules that cause common complex diseases. However, the use of specialized technology, varying study designs, and misconceptions about the role of novel findings in genetics has led to confusion among basic scientists and health care professionals alike regarding the importance of these findings in molecular...
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