Article
Glaucoma Genetics: Lessons Learned and the New Frontier.
Ophthalmology. Glaucoma - 1 Jan 2025
Wiggs Janey L, Pasquale Louis R
Abstract excerpt
Genetic analyses have led to the identification of 12 genes primarily responsible for early-onset glaucoma and hundreds of genomic loci influencing adult-onset disease risk. Childhood glaucoma genes encode for proteins involved in ocular development and extracellular matrix, while genetic factors influencing adult-onset disease are involved in a number of biological pathways and processes. Genes responsible for...
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