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Article

The use of high-dimensional biology (genomics, transcriptomics, proteomics, and metabolomics) to understand the preterm parturition syndrome.

BJOG : an international journal of obstetrics and gynaecology - 1 Dec 2006

Romero R, Espinoza J, Gotsch F, Kusanovic J P, Friel L A, Erez O, Mazaki-Tovi S, Than N G, Hassan S, Tromp G

Abstract excerpt

High-dimensional biology (HDB) refers to the simultaneous study of the genetic variants (DNA variation), transcription (messenger RNA [mRNA]), peptides and proteins, and metabolites of an organ, tissue, or an organism in health and disease. The fundamental premise is that the evolutionary complexity of biological systems renders them difficult to comprehensively understand using only a reductionist approach. Such...

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Identifiers

PMID: 17206980
DOI: 10.1111/j.1471-0528.2006.01150.x
PMCID: PMC7062297

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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