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Article

CRISP2 Is a Regulator of Multiple Aspects of Sperm Function and Male Fertility

13 Feb 2019

Abstract excerpt

The cysteine-rich secretory proteins (CRISPs) are a group of proteins that show a pronounced expression biased to the male reproductive tract. Although sperm encounter CRISPs at virtually all phases of sperm development and maturation, CRISP2 is the sole CRISP produced during spermatogenesis, wherein it is incorporated into the developing sperm head and tail. In this study we tested the necessity for CRISP2 in...

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PMID: 30759213
DOI: 10.1210/en.2018-01076

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