Article
flp gene disruption in a parasitic nematode reveals motor dysfunction and unusual neuronal sensitivity to RNA interference.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Apr 2007
Kimber Michael J, McKinney Susan, McMaster Steven, Day Tim A, Fleming Colin C, Maule Aaron G
Abstract excerpt
The potato cyst nematode Globodera pallida is a serious pest of potato crops. Nematode FMRFamide-like peptides (FLPs) are one of the most diverse neuropeptide families known, and modulate sensory and motor functions. As neuromuscular function is a well-established target for parasite control, parasitic nematode FLP signaling has significant potential in novel control strategies. In the absence of transgenic...
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