Article
A novel statistical method to estimate the effective SNP size in vertebrate genomes and categorized genomic regions.
BMC genomics - 29 Dec 2006
Seo Daekwan, Jiang Cizhong, Zhao Zhongming
Abstract excerpt
BACKGROUND: The local environment of single nucleotide polymorphisms (SNPs) contains abundant genetic information for the study of mechanisms of mutation, genome evolution, and causes of diseases. Recent studies revealed that neighboring-nucleotide biases on SNPs were strong and the genome-wide bias patterns could be represented by a small subset of the total SNPs. It remains unsolved for the estimation of the...
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