Article
A functional polymorphism in the manganese superoxide dismutase gene and diabetic nephropathy.
Diabetes - 1 Jan 2007
Möllsten Anna, Marklund Stefan L, Wessman Maija, Svensson Maria, Forsblom Carol, Parkkonen Maikki, Brismar Kerstin, Groop Per-Henrik, Dahlquist Gisela
Abstract excerpt
Oxidative stress has been suggested to contribute to the development of diabetic nephropathy. Manganese superoxide dismutase (MnSOD) protects the cells from oxidative damage by scavenging free radicals. The demand for antioxidants is increased by smoking, which could disturb the balance between antioxidants and radicals. The present study aimed to determine whether a valine/alanine polymorphism in MnSOD (V16A,...
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