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Multiplex PCR for rapid detection of genes encoding acquired metallo- -lactamases

13 Nov 2006

Abstract excerpt

Sir, Carbapenems are considered a last-line agent for the treatment of serious Gram-negative sepsis. Metallo-β-lactamases (MBLs) hydrolyse carbapenems efficiently and, when present, can undermine carbapenem therapy.1 Acquired MBLs have been reported mainly in clinical isolates of Pseudomonas aeruginosa and Acinetobacter spp., sometimes from major clonal outbreaks, as well as in other non-fermenters; they have...

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PMID: 17185300
DOI: 10.1093/jac/dkl481

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