Phenotypic and genotypic characterization of clinical carbapenem-resistant Acinetobacter species harboring the metallo-beta-lactamases IMP-8 or NDM-1 in China.

doi:10.1128/spectrum.01158-24

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Phenotypic and genotypic characterization of clinical carbapenem-resistant Acinetobacter species harboring the metallo-beta-lactamases IMP-8 or NDM-1 in China.

Microbiology spectrum - 4 Feb 2025

Xu Qingye, Mu Xinli, He Jintao, Liu Haiyang, Liu Xiaochen, Wang Yanfei, Hua Xiaoting, Yu Yunsong

Abstract excerpt

Carbapenem-resistant Acinetobacter spp. pose a significant challenge in clinical settings due to limited treatment options for nosocomial infections. Carbapenem-hydrolyzing class D beta-lactamases are the primary cause for carbapenem resistance, while metallo-beta-lactamases (MBLs) New Delhi metallo beta-lactamase (NDM) and imipenemase (IMP) also contribute. This study investigated five MBL-producing...

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Topics

beta-Lactamases
China
Carbapenems
Humans
Anti-Bacterial Agents
Acinetobacter Infections

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Acinetobacter

Microbial Sensitivity Tests

Plasmids

Genotype

Phenotype

Drug Resistance, Multiple, Bacterial

Bacterial Proteins

Whole Genome Sequencing

Integrons

Source

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Identifiers

PMID: 39727411
DOI: 10.1128/spectrum.01158-24
PMCID: PMC11792499

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