Article
Differential localization of autolyzed calpains 1 and 2 in slow and fast skeletal muscles in the early phase of atrophy.
American journal of physiology. Cell physiology - 1 May 2007
Vermaelen Marianne, Sirvent Pascal, Raynaud Fabrice, Astier Catherine, Mercier Jacques, Lacampagne Alain, Cazorla Olivier
Abstract excerpt
Calpains have been proposed to be involved in the cytoskeletal remodeling and wasting of skeletal muscle. However, limited data are available about the specific involvement of each calpain in the early stages of muscle atrophy. The aims of this study were to determine whether calpains 1 and 2 are autolyzed after a short period of muscle disuse, and, if so, where in the myofibers the autolyzed products are...
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