Article
The Lyme disease agent Borrelia burgdorferi requires BB0690, a Dps homologue, to persist within ticks.
Molecular microbiology - 1 Feb 2007
Li Xin, Pal Utpal, Ramamoorthi Nandhini, Liu Xianzhong, Desrosiers Daniel C, Eggers Christian H, Anderson John F, Radolf Justin D, Fikrig Erol
Abstract excerpt
Borrelia burgdorferi survives in an enzootic cycle, and Dps proteins protect DNA against damage during starvation or oxidative stress. The role of a Dps homologue encoded by Borrelia in spirochaete survival was assessed. Dps-deficient spirochaetes were infectious in mice via needle-inoculation at...
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