Article
HOXA1 gene variants influence head growth rates in humans.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Apr 2007
Muscarella Lucia Anna, Guarnieri Vito, Sacco Roberto, Militerni Roberto, Bravaccio Carmela, Trillo Simona, Schneider Cindy, Melmed Raun, Elia Maurizio, Mascia Maria Lucia, Rucci Emanuela, Piemontese Maria Rosaria, D'Agruma Leonardo, Persico Antonio M
Abstract excerpt
We previously described a significant association between the HOXA1 G218 allele and increased head circumference in autism [Conciatori et al. (2004); Biol Psychiatry 55:413-419]. The present study reveals identical effects also in normal children. HOXA1 A218G alleles and sex explain as much as 10.9 and 6.8% of the variance in head circumference in 142 pediatric controls and in 191 autistic children, aged 3-16...
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