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Article

Genetics of early-life head circumference and genetic correlations with neurological, psychiatric and cognitive outcomes.

BMC medical genomics - 4 Jun 2022

Vogelezang Suzanne, Bradfield Jonathan P, Grant Struan F A, Felix Janine F, Jaddoe Vincent W V

Abstract excerpt

BACKGROUND: Head circumference is associated with intelligence and tracks from childhood into adulthood. METHODS: We performed a genome-wide association study meta-analysis and follow-up of head circumference in a total of 29,192 participants between 6 and 30 months of age. RESULTS: Seven loci reached genome-wide significance in the combined discovery and replication analysis of which three loci near ARFGEF2,...

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Identifiers

PMID: 35659227
DOI: 10.1186/s12920-022-01281-1
PMCID: PMC9166310

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