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Article

A patient with hyper-IgD syndrome responding to anti-TNF treatment.

Clinical rheumatology - 1 Oct 2007

Demirkaya Erkan, Caglar M Kazim, Waterham Hans R, Topaloglu Rezan, Ozen Seza

Abstract excerpt

The hyperimmunoglobulinemia D periodic fever syndrome (HIDS) is caused by recessive mutations in the mevalonate kinase gene, which encodes an enzyme involved in cholesterol and nonsterol isoprenoid biosynthesis. The pathogenesis and treatment remains unclear. We describe a 6-year-old Turkish girl with severe disease. Her clinical features were accompanied with very high acute-phase reactants including a very high...

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Source

Identifiers

PMID: 17171314
DOI: 10.1007/s10067-006-0501-1

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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