Article
Molecular biology of T-type calcium channels.
CNS & neurological disorders drug targets - 1 Dec 2006
Perez-Reyes E, Lory P
Abstract excerpt
This review summarizes recent progress on the molecular biology of low voltage-gated, T-type, calcium channels. The genes encoding these channels were identified by molecular cloning of cDNAs that were similar in sequence to the alpha1 subunit of high voltage-activated Ca2+ channels. Three T-channel genes were identified: CACNA1G, encoding Cav3.1; CACNA1H, encoding Cav3.2; and CACNA1I, encoding Cav3.3. Recent...
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