Article
The impact of cell heterogeneity and immunophenotypic changes on monitoring minimal residual disease in acute myeloid leukemia.
Neoplasma - 1 Jan 2006
Zelezníková T, Babusíková O
Abstract excerpt
Monitoring of minimal residual disease (MRD) becomes increasingly important for the more accurate stratification of the therapy in acute leukemia. The purpose of this study was to characterize in detail the phenotypes of heterogeneous population in various AML subtypes and to identify the leukemia associated aberrant phenotype (LAP) in individual patients with AML for precise investigation of MRD. The impact of...
Topics
- Acute Disease
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Blast Crisis
- Bone Marrow
- Child
- Child, Preschool
- Female
- Flow Cytometry
- Humans
