Article
Susceptibility to pre-eclampsia is associated with multiple genetic polymorphisms in maternal biotransformation enzymes.
Gynecologic and obstetric investigation - 1 Jan 2007
Zusterzeel Petra L M, Peters Wilbert H M, Burton Graham J, Visser Willy, Roelofs Hennie M J, Steegers Eric A P
Abstract excerpt
BACKGROUND/AIMS: Probably no single gene is responsible for pre-eclampsia, but the disease merely is the result of polymorphisms in several genes in association with environmental factors. We therefore studied the simultaneous occurrence of several genetic polymorphisms in biotransformation enzymes in women who had developed pre- eclampsia, either with or without the HELLP syndrome, in comparison with healthy...
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