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Article

Polymorphism in the glutathione S-transferase P1 gene and risk for preeclampsia

1 Jul 2000

Abstract excerpt

OBJECTIVE: To determine whether genetic variability in biotransformation enzymes contributes to individual differences in susceptibility to preeclampsia or the syndrome of hemolysis, elevated liver enzymes, and low platelets (HELLP). METHODS: Polymorphisms in the genes of glutathione S-transferases and cytochrome P-450 1A1 were assessed by polymerase chain reaction in 170 nonpregnant women with a history of...

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PMID: 10862841
DOI: 10.1016/s0029-7844(00)00845-0

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