[Inducement effect of matrine on phenotype changes of rat hepatic oval cells].

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Article

[Inducement effect of matrine on phenotype changes of rat hepatic oval cells].

Ai zheng = Aizheng = Chinese journal of cancer - 1 Dec 2006

Yang Zhi-Yun, Yao Shu-Kun, Yin Fei, Xiu He-Ming

Abstract excerpt

BACKGROUND & OBJECTIVE: Atypical dysplasia of oval cells plays a crucial role in the pathogenesis of hepatocellular carcinoma (HCC). To prevent oval cells from carcinogenesis or induce them to differenciate into hepatocytes will become an effective way for chemical treatment of HCC. This study was to construct a rat hepatic oval cell proliferation model, and observe the inducement effect of matrine on phenotype...

Topics

2-Acetylaminofluorene
Adenosine Triphosphatases
Alkaloids
Animals
Antineoplastic Agents, Phytogenic
Cell Proliferation
Dose-Response Relationship, Drug
Hepatectomy
Hepatocytes
Male
Phenotype
Quinolizines
Random Allocation
Rats
Rats, Sprague-Dawley
Thy-1 Antigens
alpha-Fetoproteins
gamma-Glutamyltransferase

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Open in PubMed

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PMID: 17166375

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