Highly sensitive detection of cytotoxicity using a modified HSP70B' promoter.

Abstract excerpt

We have previously found that the DNA fragment from nucleotides (nts) -287 to +110 in the HSP70B' gene is a functional promoter responding to Cadmium Chloride-induced cytotoxicity (Wada et al., Biotechnol Bioeng, 92, 410-415, 2005). In order to increase the cytotoxic response of this promoter, we first determined the location of the cytotoxic responding element (CRE) and then constructed tandem repeats of the CRE...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Biological Assay
• Share to Carcinoma, Hepatocellular
• Share to Genes, Reporter