Article
X-monosomy effects on visuospatial attention in mice: a candidate gene and implications for Turner syndrome and attention deficit hyperactivity disorder.
Biological psychiatry - 15 Jun 2007
Davies William, Humby Trevor, Isles Anthony R, Burgoyne Paul S, Wilkinson Lawrence S
Abstract excerpt
BACKGROUND: The loss of all, or part of an X chromosome, in Turner syndrome (TS, 45,XO) results in deficits in attentional functioning. METHODS: Using a 39,XO mouse model, we tested the hypothesis that X-monosomy and/or parental origin of the single X chromosome may influence visuospatial attentional functioning in a 5-choice serial reaction time task (5-CSRTT). RESULTS: Under attentionally demanding conditions...
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