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Article

[Mutation screening in Angiotensin II receptors, AGTR1 and AGTR2, and evaluation of AGTR1 polymorphisms C573T and A1166C in patients with premature adrenarche].

Arquivos brasileiros de endocrinologia e metabologia - 1 Oct 2006

Moura Mônica S F, de Melo Mônica B, Longui Carlos Alberto, Rocha Mylene N, Monte Osmar

Abstract excerpt

Precocious pubarche is the appearance of pubic hair before the age of 8 years in girls and 9 years in boys. The most frequent etiology is idiopathic precocious adrenarche, suggested, after long-term follow-up, to be associated with metabolic syndrome. One of the factors involved in the genesis of precocious adrenarche is Angiotensin II (Ang II), which promotes cell proliferation and steroidogenesis through type 1...

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Source

Identifiers

PMID: 17160213
DOI: 10.1590/s0004-27302006000500010

Genes

AGTR1
AGTR2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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[Mutation screening in Angiotensin II receptors, AGTR1 and AGTR2, and evaluation of AGTR1 polymorphisms C573T and A1166C in patients with premature adrenarche].PMID 17160213Read ↗

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Identification of two AGTR2 mutations in male patients with non-syndromic mental retardation.Semantic proximity Read ↗

ACTH receptor promoter polymorphism associates with severity of premature adrenarche and modulates hypothalamo-pituitary-adrenal axis in children.Semantic proximity Read ↗

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