Evolutionary mechanisms of persistence and diversification of a calicivirus within endemically infected natural host populations.

Abstract excerpt

In order to understand the evolutionary mechanisms of persistence and diversification within the Caliciviridae, we have been exploiting endemic infection of feline calicivirus within five geographically distinct household groups of cats. By sequencing immunodominant and variable regions of the capsid gene, we identified the relative contribution of the different evolutionary processes employed by the virus to...

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