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Article

A pedigree-analysis approach to the descriptive epidemiology of autosomal-recessive disorders.

Preventive veterinary medicine - 17 Mar 2007

Man W Y N, Nicholas F W, James J W

Abstract excerpt

We describe a pedigree-analysis approach to estimating descriptive epidemiological parameters for autosomal-recessive disorders when the ancestral source of the disorder is known. We show that the expected frequency of carriers in a cohort equals the gene contribution of the ancestral source to that cohort, which is equivalent to the direct (additive) genetic relationship of that ancestor to the cohort. Also, the...

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PMID: 17126430
DOI: 10.1016/j.prevetmed.2006.10.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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