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Liver Fibrosis and Body Mass Index Predict Hepatocarcinogenesis following Eradication of Hepatitis C Virus RNA by Direct-Acting Antivirals.

Oncology - 1 Jan 2016

Akuta Norio, Kobayashi Masahiro, Suzuki Fumitaka, Sezaki Hitomi, Fujiyama Shunichiro, Kawamura Yusuke, Hosaka Tetsuya, Kobayashi Mariko, Saitoh Satoshi, Suzuki Yoshiyuki, Arase Yasuji, Ikeda Kenji, Kumada Hiromitsu

Abstract excerpt

BACKGROUND AND AIMS: Predictive factors for hepatocarcinogenesis following eradication of hepatitis C virus (HCV) RNA by antiviral therapy with direct-acting antivirals are unknown. Especially the impact of treatment with or without interferon on hepatocarcinogenesis is not clear. METHODS: A total of 958 patients with HCV genotype 1-related chronic liver disease and a sustained virological response defined as...

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PMID: 27694754
DOI: 10.1159/000450551

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