Article
Short- and long-term outcome of interferon therapy for chronic hepatitis B infection.
World journal of gastroenterology - 7 Oct 2014
Seo Yasushi, Yano Yoshihiko
Abstract excerpt
Hepatitis B virus (HBV) infection is a serious clinical problem worldwide. Conventional interferon (IFN)-α has been approved for the treatment of chronic hepatitis B (CHB). Short-term studies have demonstrated that IFN-based therapy is moderately effective in inducing the loss of hepatitis e antigen (HBeAg) or seroconversion (30%-40%) in HBeAg-positive patients and also produces sustained HBV DNA suppression...
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