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Article

Point mutations in the beta-subunit of cytochrome b558 leading to X-linked chronic granulomatous disease.

Blood - 1 Jun 1991

Bolscher B G, de Boer M, de Klein A, Weening R S, Roos D

Abstract excerpt

The NADPH:O2 oxidoreductase of phagocytic leukocytes is an important enzyme for the bactericidal activity of these cells. Cytochrome b558 is a membrane component of this enzyme. In X-linked chronic granulomatous disease (Xb- CGD) the phagocytes are defective in the beta-subunit (gp91-phox) of this cytochrome. We have studied the genetic defect in a group of six X-linked CGD patients characterized by complete or...

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PMID: 1710153

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Point mutations in the beta-subunit of cytochrome b558 leading to X-linked chronic granulomatous disease.PMID 1710153Read ↗

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