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Article

A "new" genetic polymorphism of a human serum protein: inter-alpha-trypsin-inhibitor.

Human genetics - 1 Jan 1990

Vogt U, Cleve H

Abstract excerpt

A new genetic polymorphism of a human serum glycoprotein, the inter-alpha-trypsin-inhibitor (ITI), has been demonstrated by population and family studies. Sera were examined after neuraminidase treatment by isoelectric focusing on agarose gels followed by immunoblotting or by immunofixation with specific ITI-antiserum. Using this method, three common ITI phenotypes 1, 1-2 and 2, as well as two further rare ITI...

Topics

Alleles
Alpha-Globulins
Austria
Female
Gene Frequency
Germany, West
Humans
Male
Pedigree
Phenotype
Polymorphism, Genetic
Trypsin Inhibitors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 1688821
DOI: 10.1007/BF00208930

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1688821-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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A "new" genetic polymorphism of a human serum protein: inter-alpha-trypsin-inhibitor.PMID 1688821Read ↗

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The ITI system in South Koreans and Iranians analysed by an improved classification procedure. Distribution of alleles and description of "new" phenotypes.Semantic proximity Read ↗

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