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Article

Electrostatic origin of the genome packing in viruses.

Proceedings of the National Academy of Sciences of the United States of America - 14 Nov 2006

Belyi Vladimir A, Muthukumar M

Abstract excerpt

Many ssRNA/ssDNA viruses bind their genome by highly basic semiflexible peptide arms of capsid proteins. Here, we show that nonspecific electrostatic interactions control both the length of the genome and genome conformations. Analysis of available experimental data shows that the genome length is linear in the net charge on the capsid peptide arms, irrespective of the actual amino acid sequence, with a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17090672
DOI: 10.1073/pnas.0608311103
PMCID: PMC1859905

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