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Bioinformatic Identification of Tandem Repeat Antigens of the <i>Leishmania donovani</i> Complex

23 Jan 2007

Abstract excerpt

With large amounts of parasite gene sequence available, additional bioinformatic tools to screen these sequences for identifying genes encoding antigens are needed. Proteins containing tandem repeat (TR) domains are often B-cell antigens, and antibody responses toward TR domains of the proteins are dominant in human infected with certain parasites. We hypothesized that antigens of serological significance could...

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PMID: 17088350
DOI: 10.1128/iai.01205-06

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