Article
Comparing tandem repeats with duplications and excisions of variable degree.
IEEE/ACM transactions on computational biology and bioinformatics - 1 Jan 2000
Sammeth Michael, Stoye Jens
Abstract excerpt
Traditional sequence comparison by alignment employs a mutation model comprised of two events, substitutions and indels (insertions or deletions) of single positions. However, modern genetic analysis knows a variety of more complex mutation events (e.g., duplications, excisions, and rearrangements), especially regarding DNA. With ever more DNA sequence data becoming available, the need to accurately compare...
Topics
- Algorithms
- Base Sequence
- Chromosome Mapping
- DNA Repair
- Evolution, Molecular
- Genetic Variation
- Molecular Sequence Data
- Sequence Alignment
- Sequence Analysis, DNA
- Tandem Repeat Sequences