Article
Mining genetic epidemiology data with Bayesian networks application to APOE gene variation and plasma lipid levels.
Journal of computational biology : a journal of computational molecular cell biology - 1 Jan 2005
Rodin Andrei, Mosley Thomas H, Clark Andrew G, Sing Charles F, Boerwinkle Eric
Abstract excerpt
There is a critical need for data-mining methods that can identify SNPs that predict among individual variation in a phenotype of interest and reverse-engineer the biological network of relationships between SNPs, phenotypes, and other factors. This problem is both challenging and important in light of the large number of SNPs in many genes of interest and across the human genome. A potentially fruitful form of...
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