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Article

Methionine synthase reductase polymorphisms are associated with serum osteocalcin levels in postmenopausal women.

Experimental & molecular medicine - 31 Oct 2006

Kim Duk Jae, Park Byung Lae, Koh Jung-Min, Kim Ghi Su, Kim Lyoung Hyo, Cheong Hyun Sup, Shin Hyoung Doo, Hong Jung-Min, Kim Tae-Ho, Shin Hong-In, Park Eui Kyun, Kim Shin-Yoon

Abstract excerpt

Homocysteine (Hcy) is thought to play an important role in the development of osteoporosis and fracture. Methionine synthase reductase (MTRR) is an enzyme involved in the conversion of Hcy to methionine. We hypothesized that certain genetic polymorphisms of MTRR leading to reduced enzyme activity may cause hyperhomocysteinemia and affect bone metabolism. We therefore examined the associations of the A66G and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17079868
DOI: 10.1038/emm.2006.61

Genes

MTRR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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