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Article

Structure of the ligand-binding domain (LBD) of human androgen receptor in complex with a selective modulator LGD2226

25 Oct 2006

Abstract excerpt

The androgen receptor (AR) is a ligand-inducible steroid hormone receptor that mediates androgen action, determining male sexual phenotypes and promoting spermatogenesis. As the androgens play a dominant role in male sexual development and function, steroidal androgen agonists have been used clinically for some years. However, there is a risk of potential side effects and most steroidal androgens cannot be dosed...

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Identifiers

PMID: 17077481
DOI: 10.1107/s1744309106039340

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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