Article
Multidrug-resistant Mycobacterium tuberculosis, Bangui, Central African Republic.
Emerging infectious diseases - 1 Sept 2006
Nouvel Laurent X, Kassa-Kelembho Eric, Dos Vultos Tiago, Zandanga Germain, Rauzier Jean, Lafoz Carmen, Martin Carlos, Blazquez Jesus, Talarmin Antoine, Gicquel Brigitte
Abstract excerpt
We investigated multidrug-resistant (MDR) Mycobacterium tuberculosis strains in Bangui, Central African Republic. We found 39.6% with the same spoligotype and synonymous single nucleotide polymorphism in the mutT1 gene. However, strains had different rpoB mutations responsible for rifampin resistance. MDR strains in Bangui may emerge preferentially from a single, MDR-prone family.
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