Article
Blood pressure regulation by CCR genes.
Clinical and experimental hypertension (New York, N.Y. : 1993) - 1 Oct 2006
Mettimano Marco, Specchia Maria Lucia, La Torre Giuseppe, Bruno Antonio, Ricciardi Gualtiero, Savi Luigi, Romano-Spica Vincenzo
Abstract excerpt
New genetic evidence strongly supports a role for the immune system in the pathogenesis of essential hypertension (EH) through chemokines and their receptors (CCR) involvement. The aim of the present study was to evaluate the possible relation between CCR2 and CCR5 alleles and blood pressure (BP) levels in hypertensive subjects. In all, 118 essential hypertensive outpatients (male 90, female 28; stage I and II;...
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