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Article

The evolution and genomic landscape of CGB1 and CGB2 genes.

Molecular and cellular endocrinology - 2 Jan 2007

Hallast Pille, Rull Kristiina, Laan Maris

Abstract excerpt

The origin of completely novel proteins is a significant question in evolution. The luteinizing hormone (LHB)/chorionic gonadotropin (CGB) gene cluster in humans contains a candidate example of this process. Two genes in this cluster (CGB1 and CGB2) exhibit nucleotide sequence similarity with the other LHB/CGB genes, but as a result of frameshifting are predicted to encode a completely novel protein. Our analysis...

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Source

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Identifiers

PMID: 17055150
DOI: 10.1016/j.mce.2005.11.049
PMCID: PMC2599907

Genes

CGB1
CGB2
LHB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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