Article
Ancient origin of placental expression in the growth hormone genes of anthropoid primates.
Proceedings of the National Academy of Sciences of the United States of America - 6 Oct 2009
Papper Zack, Jameson Natalie M, Romero Roberto, Weckle Amy L, Mittal Pooja, Benirschke Kurt, Santolaya-Forgas Joaquin, Uddin Monica, Haig David, Goodman Morris, Wildman Derek E
Abstract excerpt
In anthropoid primates, growth hormone (GH) genes have undergone at least 2 independent locus expansions, one in platyrrhines (New World monkeys) and another in catarrhines (Old World monkeys and apes). In catarrhines, the GH cluster has a pituitary-expressed gene called GH1; the remaining GH genes include placental GHs and placental lactogens. Here, we provide cDNA sequence evidence that the platyrrhine GH...
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