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Article

Computational study of the interaction between TIBO inhibitors and Y181 (C181), K101, and Y188 amino acids.

The journal of physical chemistry. B - 26 Oct 2006

Freitas Renato F, Galembeck Sérgio E

Abstract excerpt

The non-nucleoside inhibitors of HIV-1 reverse transcriptase (NNRTIs) are an important class of drugs employed in anti-HIV chemotherapy. TIBO compounds, which belong to the NNRTIs class, are potent inhibitors of the HIV-1 reverse transcriptase enzyme (HIV-1 RT). However, mutations in the amino ac...

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Identifiers

PMID: 17048958
DOI: 10.1021/jp063058u

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17048958-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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