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Article

The role of trypsin, trypsin inhibitor, and trypsin receptor in the onset and aggravation of pancreatitis.

Journal of gastroenterology - 1 Sept 2006

Hirota Masahiko, Ohmuraya Masaki, Baba Hideo

Abstract excerpt

Trypsin activity is properly suppressed in the pancreatic acinar cells under normal conditions. A small amount of trypsinogen is converted to active trypsin and inactivated by pancreatic secretory trypsin inhibitor (PSTI), thereby preventing damage to pancreatic acinar cells as a first line of defense. However, if trypsin activation (due to excessive stimulation of pancreatic acinar cells) exceeds the capacity of...

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Identifiers

PMID: 17048046
DOI: 10.1007/s00535-006-1874-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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