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Article

Ultrastructural changes in lumbar spinal cord in transgenic SOD1G93A rats.

Folia neuropathologica - 1 Jan 2006

Fidziańska Anna, Gadamski Roman, Rafałowska Janina, Chrzanowska Hanna, Grieb Paweł

Abstract excerpt

The purpose of this study was to determine structural changes which trigger the onset and progression of amyotrophic lateral sclerosis in rats expressing a human SOD1 transgene with mutation G93A. Lumbar spinal cord of affected rats in early and late presymptomatic (PM, 60 and 93 days of age) and symptomatic (S, 120 days of age) stage of the disease were analyzed ultrastructurally. At 60 days the structure of...

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Source

Identifiers

PMID: 17039412

Genes

SOD1

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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